Headlines like “A cardiologist warns: these 5 medications increase the risk of heart attack and stroke in older people” are often oversimplified. The reality is that the benefits of a medication frequently outweigh its risks, and people should not stop prescribed medications without consulting their healthcare provider.
That said, some medications may increase cardiovascular risk in certain people or require extra caution in older adults.
1. Some NSAID pain relievers
Examples:
- Ibuprofen
- Diclofenac
- High-dose naproxen (risk varies by drug and dose)
These can increase the risk of heart attack, stroke, high blood pressure, and heart failure, especially with long-term or high-dose use.
2. Some decongestants
Examples:
- Pseudoephedrine
- Phenylephrine
These can raise blood pressure and heart rate, so they may not be suitable for people with uncontrolled hypertension or certain heart conditions.
3. Certain hormone therapies
Some forms of estrogen-containing hormone therapy may increase the risk of blood clots and stroke in some people, depending on age, health history, and how the medication is used.
4. Certain stimulants
Medications used for conditions such as ADHD or some weight-loss drugs can increase heart rate and blood pressure, particularly in people with existing cardiovascular disease.
5. Some diabetes medications
Most modern diabetes medications are safe and some even reduce cardiovascular risk. However, certain older medications or specific situations may require monitoring, so treatment should always be individualized.
Important points
Older adults may be more sensitive to medication side effects because of age-related changes in kidney function, liver function, and interactions from taking multiple medicines.
If you:
- Have heart disease
- Have had a heart attack or stroke
- Have high blood pressure
- Are over 65 and take several medications
it’s a good idea to review your medications periodically with your healthcare provider or pharmacist.
Do not stop taking any prescribed medication based on a headline alone. Stopping medicines such as blood pressure drugs, cholesterol-lowering drugs, or blood thinners without medical advice can increase your risk of serious cardiovascular events.
