The claim “Eight pills you shouldn’t take because they damage your kidneys” is often presented in a frightening way, but the truth is more nuanced: many medicines are safe when used correctly, yet some can stress the kidneys in certain people—especially at high doses, with long-term use, dehydration, or existing kidney disease.
Examples of medicines that can affect kidney function include:
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Examples: ibuprofen, naproxen, diclofenac
- Can reduce blood flow to the kidneys and increase risk of kidney injury, especially with frequent use, older age, dehydration, or kidney disease.
- Certain antibiotics
- Some antibiotics (such as aminoglycosides) can be harmful to the kidneys in some situations and require monitoring.
- Some acid-reducing medicines
- Long-term use of certain proton pump inhibitors (PPIs) has been associated in studies with kidney problems in some people.
- Certain blood pressure medicines (in specific situations)
- ACE inhibitors and ARBs can change kidney blood flow. They are often kidney-protective in conditions like diabetes, but kidney function and potassium levels may need monitoring.
- Diuretics (“water pills”)
- Can affect kidney function if they cause dehydration or electrolyte changes.
- Some antiviral medications
- Certain antivirals can affect kidneys and may require dose adjustments.
- Some chemotherapy medicines
- Several cancer treatments can be kidney-toxic and are monitored closely.
- High-dose supplements or “natural” products
- Some herbal products and excessive doses of certain supplements can harm kidneys or interact with medications.
Protect your kidneys by:
- Avoiding frequent self-use of painkillers without medical advice.
- Drinking enough fluids, especially during illness or heat.
- Telling healthcare professionals about all medicines and supplements you take.
- Checking kidney function if you have diabetes, high blood pressure, or kidney risk factors.
Do not stop prescribed medicines on your own. Many medications that require monitoring are also important for treating serious conditions.
If you tell me your age and the medicines or supplements you currently take, I can help identify which ones may need kidney monitoring.
