Claims like “these 5 medications increase the risk of heart attack and stroke in older people” are often based on real safety concerns, but the headline can be misleading. The risk usually depends on the individual’s health, dosage, and duration of use—not everyone taking these medications is at high risk.
Some medication classes that cardiologists commonly advise older adults to discuss with their healthcare provider include:
- Ibuprofen, Naproxen, and Diclofenac (NSAIDs)
- Long-term or high-dose use can increase the risk of heart attack, stroke, heart failure, and elevated blood pressure, especially in people with existing cardiovascular disease.
- Celecoxib
- This prescription NSAID may also increase cardiovascular risk in some patients, particularly at higher doses.
- Pseudoephedrine
- Commonly found in cold and sinus medications, it can raise blood pressure and heart rate, making it less suitable for some people with heart disease.
- Testosterone
- Testosterone therapy has been linked to cardiovascular concerns in certain groups, although recent research suggests the risk varies depending on the patient’s health and how the medication is used.
- Estrogen-containing hormone therapy, such as Conjugated estrogens
- In some older women, particularly when started years after menopause, hormone therapy may increase the risk of stroke or blood clots.
Important points
- Do not stop any prescribed medication on your own. Suddenly stopping some medicines can be more dangerous than continuing them.
- Many people take these medications safely because their healthcare provider has determined that the benefits outweigh the risks.
- If you’re over 65 or have heart disease, high blood pressure, diabetes, kidney disease, or a history of stroke, it’s worth asking your healthcare provider or pharmacist to review all of your medications for cardiovascular safety.
If you’re referring to a specific article or video with this headline, share the link or a screenshot, and I can explain whether its claims are supported by medical evidence.